DPH2 Human
Product Sizes
1 µg
£452.00
32-13198-1UG
5 µg
£528.00
32-13198-5UG
About this Product
- SKU:
- 32-13198
- Additional Names:
- DPH2 Homolog; S-Adenosyl-L-Methionine:L-Histidine 3-Amino-3-Carboxypropyltransferase 2; Diphtheria Toxin Resistance Protein 2; Diphthamide Biosynthesis Protein 2; DPH2L2; Diptheria Toxin Resistance Protein Required For Diphthamide Biosynthesis-Like 2; 2-(3-Amino-3-Carboxypropyl)Histidine Synthase S
- Extra Details:
- Source: Sf9; Baculovirus cells.Sterile filtered colorless solution.Diphthamide biosynthesis protein 2 (DPH2) is a homodimer and each of its monomers can bind a [4Fe-4S] cluster. DPH2 is the target of ADP ribosylating diphtheria toxin (DT) and Pseudomonas exotoxin A (PE). DPH2 was identified by its ability to complement a diphthamide mutant strain; and thus serves in diphthamide biosynthesis. The loss of DPH2 pre-activates NF-kB and death receptor pathways and renders MCF7 cells hypersensitive to tumor necrosis factor. DPH2 Human Recombinant produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 497 amino acids (1-489a.a.) and having a molecular mass of 53.1kDa (Molecular size on SDS-PAGE will appear at approximately 50-70kDa). DPH2 is expressed with an 8 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Purification:
- Greater than 85.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
