CLEC5A Human; Sf9
Product Sizes
1 µg
£452.00
32-13160-1UG
5 µg
£528.00
32-13160-5UG
About this Product
- SKU:
- 32-13160
- Additional Names:
- C-type lectin domain family 5 member A ; CLECSF5; MDL-1; MDL1; C-type lectin superfamily member 5; Myeloid DAP12-associating lectin 1.
- Extra Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered clear solution.C-type lectin domain family 5-member A isoform 1 (CLEC5A) is part of the CTL/CTLD superfamily which carry various functions; for instance cell-cell signaling; cell adhesion; glycoprotein turnover; in addition to their inflammation & immune response abilities. CLEC5A operates as a cell attachment receptor for all 4 serotypes of Dengue virus in addition to Japanese encephalitis virus. CLEC5A binds to the dengue virus and it triggers signaling through the phosphylation of TYROBP; as a result no viral entrance occurs; however this interaction does stimulate proinflammatory cytokine release. CLEC5A preforms as a positive regulator of osteoclastogenesis and also a main regulator of synovial injury & bone erosion for the period of autoimmune joint inflammation.CLEC5A produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain (28-188 a.a.) and fused to a 9 aa His Tag at C-terminus containing a total of 170 amino acids and having a molecular mass of 19.5kDa.CLEC5A shows multiple bands between 28-40kDa on SDS-PAGE; reducing conditions and purified by proprietary chromatographic techniques.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
