CLEC5A Human
Product Sizes
2 µg
£452.00
32-13159-2UG
10 µg
£528.00
32-13159-10UG
About this Product
- SKU:
- 32-13159
- Additional Names:
- C-type lectin domain family 5 member A ; CLECSF5; MDL-1; MDL1; C-type lectin superfamily member 5; Myeloid DAP12-associating lectin 1.
- Extra Details:
- Source: Escherichia Coli.Sterile Filtered clear solution.C-type lectin domain family 5-member A isoform 1 (CLEC5A) is part of the CTL/CTLD superfamily which carry various functions; for instance cell-cell signaling; cell adhesion; glycoprotein turnover; in addition to their inflammation & immune response abilities. CLEC5A operates as a cell attachment receptor for all 4 serotypes of Dengue virus in addition to Japanese encephalitis virus. CLEC5A binds to the dengue virus and it triggers signaling through the phosphylation of TYROBP; as a result no viral entrance occurs; however this interaction does stimulate proinflammatory cytokine release. CLEC5A preforms as a positive regulator of osteoclastogenesis and also a main regulator of synovial injury & bone erosion for the period of autoimmune joint inflammation.CLEC5A Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 184 amino acids (28-188 a.a) and having a molecular mass of 20.8kDa.CLEC5A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
- Purification:
- Greater than 80.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
