CD58 Human; Sf9
Product Sizes
2 µg
£452.00
32-13113-2UG
10 µg
£528.00
32-13113-10UG
About this Product
- SKU:
- 32-13113
- Additional Names:
- Lymphocyte function-associated antigen 3 isoform 1; CD58; ag3; LFA-3; LFA3; Surface glycoprotein LFA-3.
- Extra Details:
- Source: Sf9; Baculovirus cells.Sterile filtered colorless solution.CD33 is putative adhesion molecule of myelomonocytic-derived cells which mediates sialic-acid dependent binding to cells. CD33 prefers to bind to alpha-2;6-linked sialic acid. The sialic acid recognition site is masked by cis interactions with sialic acids on the same cell surface. In the immune response; CD33 perform as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatases through their SH2 domains which block signal transduction through dephosphorylation of signaling molecules. In addition; CD33 induces apoptosis in acute myeloid leukemia.CD58 produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 196 amino acids (29-215a.a.) and having a molecular mass of 22.5kDa. (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).CD58 is expressed with a 9 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Purification:
- Greater than 95.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
