CD33 Human; Sf9
Product Sizes
2 µg
£452.00
32-13102-2UG
10 µg
£528.00
32-13102-10UG
About this Product
- SKU:
- 32-13102
- Additional Names:
- Myeloid cell surface antigen CD33 isoform 1; CD33; FLJ00391; p67; SIGLEC-3; SIGLEC3; gp67.
- Extra Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered colorless solution.CD33 is putative adhesion molecule of myelomonocytic-derived cells which mediates sialic-acid dependent binding to cells. CD33 prefers to bind to alpha-2;6-linked sialic acid. The sialic acid recognition site is masked by cis interactions with sialic acids on the same cell surface. In the immune response; CD33 perform as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatases through their SH2 domains which block signal transduction through dephosphorylation of signaling molecules. In addition; CD33 induces apoptosis in acute myeloid leukemia.CD33 produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain (18-259 a.a.) and fused to a 239 aa hIgG-His Tag at C-terminus containing a total of 484 amino acids and having a molecular mass of 54kDa. CD33 shows multiple bands between 50-70kDa on SDS-PAGE; reducing conditions and purified by proprietary chromatographic techniques.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
