FGF12 Recombinant Protein
Product Sizes
10 µg
£528.00
32-1182-10UG
About this Product
- SKU:
- 32-1182
- Additional Names:
- FGF-12||FGF12||FGF12B||FHF1||Fibroblast growth factor 12||Fibroblast growth factor homologous factor 1||FHF-1||Myocyte-activating factor.
- Extra Details:
- Source : Escherichia Coli. The FGF-12 Human recombinant protein is a single; non-glycosylated polypeptide chain produced in E. coli; having a molecular weight of 22.6kDa and containing 201 amino acids (1-181). The FGF12 is fused to a 20 amino acid His tag at the N-terminus. FGF12 is part of the Fibroblast Growth Factor (FGF) family which has a vast mitogenic and cell survival functions; and play a role in a range of biological activities; among them are embryonic development; cell growth; morphogenesis; tissue repair; tumor growth; and invasion. FGF-12 doesn't obtain the N-terminal signal sequence present in the majority of the FGF family members; but it contains clusters of basic residues that act as a nuclear localization signal. When transfected into mammalian cells; FGF12 accumulated in the nucleus; but was not secreted. FGF12 is involved in nervous system development and function. FGF12 binds to IB2 (islet brain-2); a cellular kinase scaffold; and voltage gated sodium channels and is also involved in intracellular signaling and ion exchange.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store FGF12 at -20[o]C. Can be stored at 4[o]C for a limited period of time of 7 days.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
