CNTF Recombinant Protein
Product Sizes
20 µg
£528.00
32-1110-20UG
About this Product
- SKU:
- 32-1110
- Additional Names:
- HCNTF||CNTF||Ciliary Neurotrophic Factor.
- Extra Details:
- Source : Escherichia Coli. Ciliary Neurotrophic Factor Recombinant Human produced in E.Coli is a single; non-glycosylated polypeptide chain containing 199 amino acids and having a molecular mass of 22706 Dalton. The CNTF is purified by proprietary chromatographic techniques. CNTF is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene; which results in aberrant splicing; leads to ciliary neurotrophic factor deficiency; but this phenotype is not causally related to neurologic disease. In addition to the predominant monocistronic transcript originating from this locus; the gene is also co-transcribed with the upstream ZFP91 gene. Co-transcription from the two loci results in a transcript that contains a complete coding region for the zinc finger protein but lacks a complete coding region for ciliary neurotrophic factor.CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
- Purification:
- Greater than 98.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized Ciliary Neurotrophic Factor although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution CNTF should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
