CLCF1 Recombinant Protein
Product Sizes
20 µg
£528.00
32-1109-20UG
About this Product
- SKU:
- 32-1109
- Additional Names:
- Cardiotrophin-like cytokine factor 1||B-cell-stimulating factor 3||BSF-3||Novel neurotrophin-1||NNT-1||CLCF1||BSF3||CLC||NNT1||NR6||CISS2.
- Extra Details:
- Source : Escherichia Coli. CLCF1 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 219 amino acids (28-225 a.a) and having a molecular mass of 24.6kDa.CLCF1 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Cardiotrophin-like cytokine factor 1 (CLCF1) is a member of the interleukin 6 family of cytokines; which are involved in cell signaling via phosphorylation of gp130. CLCF1 has a sequence of 225 amino acids with a 27 aa signal peptide; having a molecular mass of 22kDa in the mature form; and the maximum homology to cardiotrophin-1 and ciliary neurotrophic factor. CLCF1 is actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. Defects in the CLCF1 gene cause cold-induced sweating syndrome 2 (CISS2). The CISS2 syndrome is typified by profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
