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APOA5 Recombinant Protein

Product Sizes
10 µg
£528.00
32-1042-10UG
About this Product
SKU:
32-1042
Additional Names:
Apolipoprotein A-V||Apo-AV||ApoA-V||Apolipoprotein A5||Regeneration-associated protein 3||APOA5||RAP3||APOAV.
Extra Details:
Source : Escherichia Coli. APOA5 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 366 amino acids (24-366 a.a.) and having a molecular mass of 41.3kDa.APOA5 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. ApoA5 is an important regulator of serum triglyceride concentrations. An ApoA5 mouse nock-out model produced an approximately four fold increase in serum triglycerides; whereas a knock-in model human ApoA5 produced 50-70% lower concentrations of mouse serum triglycerides. Furthermore; peroxisome proliferators-activated receptoragonists; which are used clinically to lower serum triglyceride concentrations; cause increased ApoA5 mRNA expression. There is very little known about ApoA5 protein in human serum. Lately; it was established that ApoA5 is present in the human serum and it can be detected by polyclonal antibodies against both the HN2 and COOH termini; but at much lower concentration than other apolipoproteins.
Purification:
Greater than 85.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg