AIF1 Recombinant Protein
Product Sizes
10 µg
£528.00
32-1025-10UG
About this Product
- SKU:
- 32-1025
- Additional Names:
- AIF-1||Allograft inflammatory factor 1||Em:AF129756.17||G1||IBA1||Ionized calcium-binding adapter molecule 1||IRT-1||Protein G1||AIF1.
- Extra Details:
- Source : E. Coli. The AIF1 Human Recombinant contains a total of 155 amino acids having a molecular Mass of 17.7kDa. The Human AIF1 is fused to a 9 amino acid long N-terminal His tag. Human AIF1 protein shares 98% homology/identity with that of rat. AIF1 is expressed in macrophages and neutrophils. The expression of AIF1 transcripts is upregulated by IFN-g in rat macrophages. AIF1 is expressed selectively in human macrophage-like cell lines; and in a subset of CD68(+) macrophages in the interstitial and perivascular spaces of human heart allografts. In quiescent cultured human vascular smooth muscle cells synthesis of AIF1 is induced by IFN-g; IL1b; and conditioned medium of T-cells. Overexpression of AIF1 in human VSMCs results in enhanced growth of these cells. AIF1 is expressed during apoptosis rat mammary gland and ventral prostate tissues. Allograft Inflammatory Factor 1 is expressed by several tumor-associated activated macrophages and microglial cells in rat and human gliomas. There is an evident relationship of AIF1-expressing activated macrophages and microglial cells with tumor malignancy in humans.
- Purification:
- Greater than 90% as determined by SDS PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For long term; store lyophilized AIF1 at -20[o]C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4[o]C for a limited period of time; it does not show any change after two weeks at 4[o]C.The lyophilized protein remains stable for 24 months when stored at -20[o]C.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
