Rat Anti-Mouse Ly-6A/E-LENA™ (Low Endotoxin No Azide) Clone: D7
Product Sizes
0.5 mg
£832.00
31-2027-0.5MG
About this Product
- SKU:
- 31-2027
- Additional Names:
- Lymphocyte antigen 6A-2/6E-1; Ly-6A.2/Ly-6E.1; Stem cell antigen 1; T-cell-activating protein; TAP; SCA-1
- translate.label.attr.clone:
- D7
- Clonality:
- Monoclonal
- Extra Details:
- Ly-6A/E; also known as Sca-1; is a member of the Ly-6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly-6.1 and Ly-6.2 allotypes. In the periphery; Ly-6A/E exhibits a pattern of expression which is based on differences between the two allotypes. Ly-6.1 strains (e.g.; A; BALB/c; CBA; C3H/He; DBA/1; NZB) have few Ly-6A/E+ resting peripheral lymphocytes whereas Ly-6.2 strains (e.g.; AKR; C57BL; C57BR; C57L; DBA/2; PL; SJL; SWR; 129) have relatively high numbers of Ly-6A/E+ lymphocytes. The expression of Ly-6A/E is dramatically upregulated in all strains upon cellular activation. Studies with the monoclonal antibody D7 suggest that Ly-6A/E may be involved in B and T lymphocyte responses and it appears that the antigen may be required for T-cell receptor-mediated T-cell activation.
- Isotype:
- Rat IgG2a; kappa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C
- Supplier:
- Abeomics
- Type:
- Assay Kits:Endotoxin / LAL
- Manufacturer's Data Sheet:download_pdf.php
