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Antibodies

Anti-Human CD183 Monoclonal Antibody FITC Conjugated (Clone: rHIQB005)

Product Sizes
100 tests
£568.00
30-2941FITC-100TESTS
About this Product
SKU:
30-2941FITC
Additional Names:
CXCR3; fusin; CKR-L2; CMKAR3; GPR9; IP10-R; MIG-R
translate.label.attr.clone:
rHIQB005
Clonality:
Monoclonal
Conjugate:
FITC
Extra Details:
Specificity: The recombinant mouse monoclonal antibody rHIQB005 recognizes an extracellular epitope on human chemokine receptor CD184. Background: CD184 is a 7-transmembrane G-protein coupled receptor for the C-X-C chemokines SDF-1 (CXCL12); MIG (CXCL9) and IP10 (CXCL10). Alternatively spliced variant CD184B serves as the high affinity receptor for PF4 (CXCL4). CD184 is expressed in hematopoietic cells; vascular endothelium; and neural tissue. It plays important roles in endothelial vascularization and central nervous system development. It can also serve as a primary receptor or a coreceptor for some HIV isolates. CD184 signaling leads to integrin activation; cytoskeletal changes and chemotactic migration. CD184 is a 7-transmembrane G-protein coupled receptor for the C-X-C chemokines SDF-1 (CXCL12); MIG (CXCL9) and IP10 (CXCL10). Alternatively spliced variant CD184B serves as the high affinity receptor for PF4 (CXCL4). CD184 is expressed in hematopoietic cells; vascular endothelium; and neural tissue. It plays important roles in endothelial vascularization and central nervous system development. It can also serve as a primary receptor or a coreceptor for some HIV isolates. CD184 signaling leads to integrin activation; cytoskeletal changes and chemotactic migration.
Host:
Mouse
Isotype:
Mouse IgG1
Purification:
Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2: Flow cytometry multicolor surface staining pattern of human lymphocytes stained using anti-human CD3 (UCHT1) APC antibody (10 μl reagent / 100 μl of peripheral whole blood) and anti-human CD183 (rHIQB005) FITC antibody (concentration in sample 1.67μg/ml).
Figure 3: Separation of human CD3 positive CD183 positive T cells (red-filled) from CD3 negative CD183 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD183 (rHIQB005) FITC antibody (concentration in sample 1.67μg/ml).
Figure 3: Separation of human CD3 positive CD183 positive T cells (red-filled) from CD3 negative CD183 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD183 (rHIQB005) FITC antibody (concentration in sample 1.67μg/ml).