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Antibodies

Anti-Human CD194 Monoclonal Antibody APC Conjugated (Clone: rHIQB002)

Product Sizes
100 tests
£605.00
30-2939APC-100TESTS
About this Product
SKU:
30-2939APC
Additional Names:
CCR4; CC-CKR-4; CKR4; CMKBR4; ChemR13; HGCN
translate.label.attr.clone:
rHIQB002
Clonality:
Monoclonal
Conjugate:
APC
Extra Details:
Specificity: The recombinant mouse monoclonal antibody rHIQB002 recognizes an extracellular epitope of human chemokine receptor CD194 (CCR4). Background: CD194 is a G-protein-coupled seven membrane-spanning transmembrane protein serving as a high affinity receptor for C-C type chemokines TARC (CCL17) and MDC (CCL22); and as a coreceptor for HIV. It is expressed by all CLA+ T cells regardless of their Th1 or Th2 phenotype; on activated Th2; Treg; and activated NK cells; basophils and macrophages. Blocking CD194 function can be used for treatment of inflammation.
Host:
Mouse
Isotype:
Mouse IgG1
Purification:
Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2: Flow cytometry multicolor surface staining pattern of human lymphocytes stained using anti-human CD3 (UCHT1) PE antibody (20 μl reagent / 100 μl of peripheral whole blood) and anti-human CD194 (rHIQB002) APC antibody (concentration in sample 0.19μg/ml).
Figure 3: Separation of human CD3 positive CD194 positive T cells (red-filled) from CD3 negative CD194 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD194 (rHIQB002) APC antibody (concentration in sample 0.19μg/ml).
Figure 3: Separation of human CD3 positive CD194 positive T cells (red-filled) from CD3 negative CD194 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD194 (rHIQB002) APC antibody (concentration in sample 0.19μg/ml).