Anti-Human CD276 Monoclonal Antibody (Clone: 7-517)
Product Sizes
0.1 mg
£532.00
30-2938-0.1MG
About this Product
- SKU:
- 30-2938
- Additional Names:
- B7H3; B7RP-2
- translate.label.attr.clone:
- 7-517
- Clonality:
- Monoclonal
- Extra Details:
- Specificity: The mouse monoclonal antibody 7-517 recognizes an extracellular epitope of human CD276 (B7H3) transmembrane glycoprotein. Background: CD276 (B7H3) is a type I transmembrane glycoprotein expressed on dendritic cells; osteoblasts; sinonasal epithelium; and upon activation (by inflammatory cytokines) in monocytes; NK cells; T cells and B cells. Although it has been described also as a costimulatory ligand; its major role seems to be inhibitory. It regullates T cell proliferation and functions; and may provide certain tumors with protection against NK cells. CD276 can be used as a marker of neuroblastoma cells in the bone marrow; which is the primary site of neuroblastoma relapse. CD276 (B7H3) is a type I transmembrane glycoprotein expressed on dendritic cells; osteoblasts; sinonasal epithelium; and upon activation (by inflammatory cytokines) in monocytes; NK cells; T cells and B cells. Although it has been described also as a costimulatory ligand; its major role seems to be inhibitory. It regullates T cell proliferation and functions; and may provide certain tumors with protection against NK cells. CD276 can be used as a marker of neuroblastoma cells in the bone marrow; which is the primary site of neuroblastoma relapse.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- monocyte-derived dendritic cells
- Isotype:
- Mouse IgG1 kappa
- Purification:
- Purified by protein-A affinity chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
