Anti-Human Fc epsilon RIa Monoclonal Antibody (Clone: AER-37 [CRA1])
Product Sizes
0.1 mg
£532.00
30-2937-0.1MG
About this Product
- SKU:
- 30-2937
- Additional Names:
- FcµR1; FCER1A
- translate.label.attr.clone:
- AER-37 [CRA1]
- Clonality:
- Monoclonal
- Extra Details:
- Specificity: The mouse monoclonal antibody AER-37 [CRA1] recognizes an extracellular epitope of the high-affinity IgE receptor I alpha subunit (Fc epsilon RIa). Background: FcµRI serves as the IgE Fc-binding subunit of the high-affinity IgE receptor; expressed on the surface of mast cells and basophils. It associates with one beta and two gamma subunits that contain ITAM sequences in their intracellular domains; that function as docking sites in the process of signalosome forming after FcµRI triggering. Attached IgE gives to the receptor specificity for particular antigens which are target of the type I allergen sensitivity or hypersensitivity reaction; and prolongs stability of the receptor on the cell surface. Under physiological conditions this system protects the body against helminths and other parasites and venom toxins; but when dysregulated; it can lead to undesired allergic reactions and anaphylactic shock.
- Format:
- Purified
- Host:
- Mouse
- Isotype:
- Mouse IgG2b kappa
- Purification:
- Purified by protein-A affinity chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
