Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

Anti-Hu CD207 (Clone 2G3) Alexa Fluor 647

Product Sizes
100 Tests
£649.00
30-2927AF647-100TESTS
About this Product
SKU:
30-2927AF647
Additional Names:
CLEC4K; langerin
translate.label.attr.clone:
2G3
Clonality:
Monoclonal
Extra Details:
CD207 is a 40 kDa type II transmembrane glycoprotein of the C-type lectin family. It binds to mannose-bearing glycoproteins and glycolipids of microbial and viral antigens; including HIV gp120. CD207 is expressed only in Langerhans cells; which are immature dendritic cells of the epidermis and mucosa; and its expression decreases during Langerhans cells maturation. Upon antigen binding CD207 localizes to the Birbeck granules; organelles present in the cytoplasm of Langerhans cells and consisting of superimposed membranes; which leads to a nonclassical antigen-processing pathway.
Host:
Mouse
Immunogen:
Fusion protein of human CD207 extracellular part and IgG Fc fragment
Isotype:
Mouse IgG1 lambda
Purification:
Purified by protein-A affinity chromatography.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
Figure 2: Flow cytometry multicolor surface staining of human stimulated (GM-CSF + IL-4) peripheral blood mononuclear cells stained using anti-human CD207 (2G3) Alexa Fluor 647 antibody (4 µl reagent per million cells in 100 µl of cell suspension) and anti-human CD11c (BU15) PE antibody (20 µl reagent per milion cells in 100 µl of cell suspension).
Figure 3: Separation of human CD11c positive CD207 positive differentiated dendritic cells (red-filled) from CD11c negative CD207 negative cell (black-dashed) in flow cytometry analysis (surface staining) of stimulated (GM-CSF + IL-4) peripheral blood mononuclear cells stained using anti-human CD207 (2G3) Alexa Fluor 647 antibody (4 µl reagent per million cells in 100 µl of cell suspension; red-filled).
Figure 3: Separation of human CD11c positive CD207 positive differentiated dendritic cells (red-filled) from CD11c negative CD207 negative cell (black-dashed) in flow cytometry analysis (surface staining) of stimulated (GM-CSF + IL-4) peripheral blood mononuclear cells stained using anti-human CD207 (2G3) Alexa Fluor 647 antibody (4 µl reagent per million cells in 100 µl of cell suspension; red-filled).