Anti-Hu CD367 PE Mab (9E8)
Product Sizes
100 Tests
£620.00
30-2917-100TESTS
About this Product
- SKU:
- 30-2917
- Additional Names:
- DCIR; CLEC4A; LLIR
- translate.label.attr.clone:
- 9E8
- Clonality:
- Monoclonal
- Conjugate:
- PE
- Extra Details:
- Specificity: The mouse monoclonal antibody 9E8 recognizes an extracellular epitope of human CD367; a type II transmembrane protein of C-lectin family; expressed mainly on antigen presenting cells. CD367 is an approximately 20-28 kDa C-type lectin with immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic part. CD367 binds in calcium-dependent manner to mannose; fucose; and weakly also to N-acetylglucosamine. It is expressed on dendritic cells; macrophages; monocytes; B cells; and neutrophils. In rheumatoid arthitis patients CD367 is expressed also on CD4+ T cells. After ligand-mediated triggering; it is internalized by clathrin-dependent endocytosis and contributes to the antigen presentation to CD8+ T cells. It may also be involved in modulation of the antigen presenting cell response.
- Host:
- Mouse
- Immunogen:
- CD367 ectodomain fused with human Fc
- Isotype:
- Mouse IgG1 kappa
- Purification:
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
