Anti-Hu CD142 APC Mab (HTF-1)
Product Sizes
100 Tests
£620.00
30-2906-100TESTS
About this Product
- SKU:
- 30-2906
- Additional Names:
- F3; tissue factor; tissue thromboplastin; coagulation factor III; TF; TFA
- translate.label.attr.clone:
- HTF-1
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- Specificity: The mouse monoclonal antibody HTF-1; also known as HTF1-7B8; recognizes an extracellular epitope of CD142 (tissue factor; coagulation factor III); a type I glycoprotein expressed on endothelial cells; monocytes; macrophages; and platelets upon induction by inflammatory mediators; and expressed constitutively by some tumors; the vasculature; placenta; kidney; and central nervous system. CD142; also known as coagulation factor III; tissue thromboplastin; and tissue factor. It is a transmembrane glycoprotein; which enables cells to initiate the blood coagulation cascades; and functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades; which circulate as nonfunctional precursors; this factor is a potent initiator that is fully functional when expressed on cell surfaces. It is the only one factor in the coagulation pathway for which a congenital deficiency has not been described.
- Host:
- Mouse
- Immunogen:
- Human brain tissue factor (CD142)
- Isotype:
- Mouse IgG1 kappa
- Purification:
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
