APC Anti-Hu CD141 Mab (M80)
Product Sizes
100 Tests
£649.00
30-2905AC-100TESTS
About this Product
- SKU:
- 30-2905AC
- Additional Names:
- Thrombomodulin; fetomodulin; THBD; THRM; THPH12; TM
- translate.label.attr.clone:
- M80
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- CD141; also known as thrombomodulin or fetomodulin; is a single chain type I transmembrane glycoprotein serving as a receptor for thrombin and as an important cofactor in the protein C anticoagulant system; but it is also involved in embryonic and atherosclerotic plaque development. CD141 is expressed mainly on macrophages; monocytes; a subpopulation of myeloid dendritic cells; on platelets and endothelial cells; but also e.g. on keratinocytes (epithelium). After binding to thrombin; CD141 activates protein C; which degrades clotting factors Va and VIIIa; and as a consequence the amount of thrombin is reduced. Mutations in the CD141 gene can cause a thromboembolic disease known as inherited thrombophilia.
- Host:
- Mouse
- Immunogen:
- MV4-11 cell line
- Isotype:
- Mouse IgG1
- Purification:
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:30-2905AC.jpg
