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Antibodies

Alexa Fluor 647 Conjugated Anti-Human C3aR Mab (Clone: HC3aRZ8)

Product Sizes
100 tests
£649.00
30-2882AF-647-100TESTS
About this Product
SKU:
30-2882AF-647
Additional Names:
AZ3B; HNFAG09
translate.label.attr.clone:
HC3aRZ8
Clonality:
Monoclonal
Extra Details:
Specificity : The mouse monoclonal antibody HC3aRZ8 recognizes an extracellular epitope of C3aR; a transmembrane chemotactic receptor for C3a anaphylatoxin. C3aR is a 7TM transmembrane protein associated with G proteins; and serves as a receptor for C3a complement fragment. It is expressed mainly on neutrophils; mast cells; basophils; eosinophils; dendritic cells; monocytes; and macrophages. Upon detection of its ligand; the activated C3aR signaling cascade results in degranulation; superoxide production; and chemotaxis.
Host:
Mouse
Immunogen:
Human C3aR transfectants
Isotype:
Mouse IgG2b
Purification:
Purified antibody is conjugated with Alexa Fluor® 647 NHS ester under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
Figure 2: Separation of human neutrophil granulocytes (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human C3aR (HC3aRZ8) Alexa Fluor® 647 antibody (4 μl reagent / 100 μl of peripheral whole blood).
Figure 2: Separation of human neutrophil granulocytes (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human C3aR (HC3aRZ8) Alexa Fluor® 647 antibody (4 μl reagent / 100 μl of peripheral whole blood).