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Antibodies

Alexa Fluor 488 Conjugated Anti-Human CD303 Mab (Clone:15E3)

Product Sizes
100 tests
£649.00
30-2877AF488-100TESTS
About this Product
SKU:
30-2877AF488
Additional Names:
BDCA2; CLEC4C; DLEC; HECL; CLECSF7;CLECSF11; PRO34150
Clonality:
Monoclonal
Extra Details:
CD303 is an approximately 38 kDa type II transmembrane glycoprotein with an extracellular C-type lectin domain. It is a specific marker of plasmacytoid dendritic cells; and plays roles in capturing of pathogen-related oligosaccharide-containing antigens by them; and in their presentation to T cells. CD303 also mediates a potent inhibition of interferon alpha/beta production in plasmacytoid dendritic cells; thus it represents a potential target for lupus erythematosus therapy. Specificity: The mouse monoclonal antibody 15E3 recognizes an extracellular epitope of human CD303; a transmembrane glycoprotein expressed on plasmacytoid dendritic cells.
Host:
Mouse
Immunogen:
CD303 ectodomain fused with human IgG Fc domain
Isotype:
Mouse IgG1 kappa
Purification:
Purified antibody is conjugated with Alexa Fluor 488 NHS ester under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2: Flow cytometry multicolor surface staining pattern of human mononuclear cells using anti-human CD303 (15E3) Alexa Fluor 488 antibody (4 µl reagent / 100 µl of peripheral whole blood) and anti-human CD123 (6H6) APC antibody (10 µl reagent / 100 µl of peripheral whole blood).
Figure 3: Separation of human CD303 positive CD123 positive plasmacytoid DC (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD303 (15E3) Alexa Fluor 488 antibody (4 µl reagent / 100 µl of peripheral whole blood).
Figure 3: Separation of human CD303 positive CD123 positive plasmacytoid DC (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD303 (15E3) Alexa Fluor 488 antibody (4 µl reagent / 100 µl of peripheral whole blood).