Anti-Human SIGLEC10 Mab (Clone: 5G6 )
Product Sizes
0.1 mg
£541.00
30-2868-0.1MG
About this Product
- SKU:
- 30-2868
- Additional Names:
- PRO940; SGL2; sialic acid binding Ig like lectin 10
- translate.label.attr.clone:
- 5G6
- Clonality:
- Monoclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Specificity : The mouse monoclonal antibody 5G6 recognizes an extracellular epitope of human SIGLEC10; a sialic acid-binding lectin expressed on subsets of human leucocytes. SIGLEC10 is a CD33-related receptor of sialoglycans; expressed on eosinophils; monocytes; a subpopulation of NK cells; and at lower level on B cells. Its murine ortholog is Siglec G. SIGLEC10 seems to act as an immunomodulatory receptor; which binds to VAP-1; a glycoprotein expressed on endothelium under inflammatory conditions. Another ligand of SIGLEC10 is CD24; a marker of poorer prognosis in carcinomas.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- SIGLEC10 extracellular domain fused with human IgG1 Fc fragment
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
