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Antibodies

Anti-Human CD1d PE MAb (Clone: 51.1)

Product Sizes
100 tests (T)
£620.00
30-2858-100TESTS
About this Product
SKU:
30-2858
Additional Names:
CD1d molecule
Clonality:
Monoclonal
Conjugate:
PE
Extra Details:
Specificity: The mouse monoclonal antibody 51.1 recognizes an extracellular epitope of CD1d; a 38 kDa transmembrane glycoprotein expressed mainly on cortical thymocytes; marginal zone B cells and other antigen presenting cells; but also i e.g. hepatitis C virus-infected livers. CD1d belongs to CD1 family of transmembrane glycoproteins; associated with beta2 microglobulin; similarly to MHC I molecules. Unlike other CD1 family members; however; CD1d can be also expressed in a non-glycosylated form; which is not associated with beta2 microglobulin. Hence it is not certain how much CD1d plays a role in the presentation of microbial lipid antigens during infection. On the other hand; it is expressed on various antigen presenting cell types. Besides it; CD1d+ thymocytes are involved in the positive selection of sublineage of NKT cells.
Host:
Mouse
Immunogen:
human CD1d
Isotype:
Mouse IgG2b kappa
Purification:
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig2: Flow cytometry multicolor surface staining of human gated lymphocytes stained using anti-human CD1d (51.1) PE antibody (10 μl reagent / 100 μl of peripheral whole blood) and anti-human CD19 (LT19) APC antibody (10 μl reagent / 100 μl of peripheral whole blood).
Fig3: Separation of human CD1d positive CD19 positive lymphocytes (red-filled) CD1d negative CD19 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD1d (51.1) PE antibody (10 μl reagent / 100 μl of peripheral whole blood).
Fig3: Separation of human CD1d positive CD19 positive lymphocytes (red-filled) CD1d negative CD19 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD1d (51.1) PE antibody (10 μl reagent / 100 μl of peripheral whole blood).