Anti-Human CD294 PE MAb (Clone :BM16)
Product Sizes
100 tests
£620.00
30-2852-100TESTS
About this Product
- SKU:
- 30-2852
- Additional Names:
- DP2; PTGDR2; DL1R; CRTH2; GPR44
- translate.label.attr.clone:
- BM16
- Clonality:
- Monoclonal
- Conjugate:
- PE
- Extra Details:
- Specificity: The rat monoclonal antibody BM16 recognizes an extracellular epitope of CD294 / CRTH2 (prostaglandin D2 receptor 2); a G-protein-coupled seven-transmembrane protein expressed on Th2 cells; peripheral blood basophils and eosinophils. CD294 (prostaglandin D2 receptor 2) is a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells; but also on eosinophils and basophils. It mediates the pro-inflammatory chemotaxis of eosinophils; basophils; and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of CD294 gene have been associated with asthma susceptibility. Outside the immune system CD294 is expressed e.g. in gut; heart; and brain. The intracellular C terminal tail contains sites for phosphorylation by protein kinase C.
- Host:
- Rat
- Immunogen:
- Human CD294 transfected rat cell line TART/B19-12.10
- Isotype:
- Rat IgG2a
- Purification:
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
