Anti-Ms CD18 Purified Low Endotoxin
Product Sizes
0.1 mg
£521.00
30-2821-0.1MG
About this Product
- SKU:
- 30-2821
- Additional Names:
- integrin subunit beta 2 Integrin beta2; Complement receptor C3 subunit beta; ITGB2
- translate.label.attr.clone:
- M18/2
- Clonality:
- Monoclonal
- Conjugate:
- Purified Low Endotoxin
- Extra Details:
- CD18; integrin beta2 subunit; forms heterodimers with four types of CD11 molecule to constitute leukocyte (beta2) integrins: alphaLbeta2 (CD11a/CD18; LFA-1); alphaMbeta2 (CD11b/CD18; Mac-1; CR3); alphaXbeta2 (CD11c/CD18) and alphaDbeta2 (CD11d/CD18). In most cases; the response mediated by the integrin is a composite of the functions of its individual subunits. These integrins are essential for proper leukocyte migration; mediating intercellular contacts. Absence of CD18 leads to leukocyte adhesion deficiency-1; severe reduction of CD18 expression leads to the development of a psoriasiform skin disease. CD18 is also a target of Mannheimia (Pasteurella) haemolytica leukotoxin and is sufficient to mediate leukotoxin-mediated cytolysis.Specificity :The rat monoclonal antibody M18/2 recognizes an extracellular epitope of CD18 antigen (integrin beta2 subunit; beta2 integrin); a 95 kDa type I transmembrane protein expressed on all leukocytes.
- Immunogen:
- Murine cytotoxic T cell glycoproteins
- Purification:
- Purified by protein-G affinity chromatography.
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Assay Kits:Endotoxin / LAL
- Manufacturer's Data Sheet:download_pdf.php
