Anti-Hu CD294 Purified
Product Sizes
0.1 mg
£541.00
30-2810-0.1MG
About this Product
- SKU:
- 30-2810
- Additional Names:
- prostaglandin D2 receptor 2 DP2; PTGDR2; DL1R; CRTH2; GPR44
- translate.label.attr.clone:
- BM16
- Clonality:
- Monoclonal
- Extra Details:
- CD294 (prostaglandin D2 receptor 2) is a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells; but also on eosinophils and basophils. It mediates the pro-inflammatory chemotaxis of eosinophils; basophils; and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of CD294 gene have been associated with asthma susceptibility. Outside the immune system CD294 is expressed e.g. in gut; heart; and brain. The intracellular C terminal tail contains sites for phosphorylation by protein kinase C.Specificity :The rat monoclonal antibody BM16 recognizes an extracellular epitope of CD294 / CRTH2 (prostaglandin D2 receptor 2); a G-protein-coupled seven-transmembrane protein expressed on Th2 cells; peripheral blood basophils and eosinophils.
- Format:
- Purified
- Immunogen:
- Human CD294 transfected rat cell line TART/B19-12.10
- Purification:
- Purified by protein-G affinity chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
