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Antibodies

Anti-Hu CD52 Purified

Product Sizes
0.1 mg
£541.00
30-2767-0.1MG
About this Product
SKU:
30-2767
Additional Names:
CD52 molecule CAMPATH-1; HE5; ESPE5
translate.label.attr.clone:
4C8
Clonality:
Monoclonal
Extra Details:
CD52 (CAMPATH-1; HE5) is a highly glycosylated GPI-anchored 21-28 kDa glycopeptide which is present at high levels on lymphocytes; macrophages; epithelial cells of male reproductive tract and mature sperm. Its 12-amino acid beckbone carries a complex N-linked carbohydrate moiety; which differs between sperm and leukocyte CD52; as well as the GPI anchor does. CD52 can be acquired by sperm cells from seminal plasma; where it is released by epithelial cells. Although CD52 is not an essential T-cell costimulator; its triggering results in activation of normal human T cells. CD52 is a very good target for antibody/complement-mediated cell lysis.Specificity :The mouse monoclonal antibody 4C8 recognizes CD52; a GPI-anchored glycopeptide expressed on the surface of lymphocytes; macrophages; epithelial cells of male reproductive tract; and mature sperms.
Format:
Purified
Immunogen:
human lymphocytes
Purification:
Purified by protein-A affinity chromatography.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody