Anti-Hu CD77 PE
Product Sizes
100 Tests
£620.00
30-2760-100TESTS
About this Product
- SKU:
- 30-2760
- Additional Names:
- globotriaosylceramide Gb3; Gal-alpha1-4Gal-beta1-4Glc-beta1-Cer; P blood group
- Clonality:
- Monoclonal
- Conjugate:
- PE
- Extra Details:
- CD77 (globotriaosylceramide Gb3); also known as the Pk blood group antigen; BLA (Burkitt´s lymphoma associated antigen); or CTH (ceramide trihexoside) is a neutral glycosphingolipid composed of three carbohydrate molecules linked to a lipid moiety in the cell membrane (Gal-alpha1-4Gal-beta1-4Glc-beta1-Cer). It is expressed on germinal center B cells; Burkitt´s lymphoma cells; it can be induced on extrafolicular B cells and it is also found on endothelia and epithelia. CD77 may be involved in elimination of germinal center B cells that fail to produce high affinity antibodies; and serves also as receptor for shiga toxin and verotoxin.Specificity :The rat monoclonal antibody 38.13 recognizes CD77 (globotriaosylceramide Gb3); a neutral glycosphingolipid expressed mainly on the surface of B cell populations; such as germinal center B cells and Burkitt´s lymphoma cells.
- Immunogen:
- Daudi cell line (Burkitt´s lymphoma)
- Purification:
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
