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Antibodies

Anti-Hu CD77 FITC

Product Sizes
100 Tests
£581.00
30-2759-100TESTS
About this Product
SKU:
30-2759
Additional Names:
globotriaosylceramide Gb3; Gal-alpha1-4Gal-beta1-4Glc-beta1-Cer; P blood group
Clonality:
Monoclonal
Conjugate:
FITC
Extra Details:
CD77 (globotriaosylceramide Gb3); also known as the Pk blood group antigen; BLA (Burkitt´s lymphoma associated antigen); or CTH (ceramide trihexoside) is a neutral glycosphingolipid composed of three carbohydrate molecules linked to a lipid moiety in the cell membrane (Gal-alpha1-4Gal-beta1-4Glc-beta1-Cer). It is expressed on germinal center B cells; Burkitt´s lymphoma cells; it can be induced on extrafolicular B cells and it is also found on endothelia and epithelia. CD77 may be involved in elimination of germinal center B cells that fail to produce high affinity antibodies; and serves also as receptor for shiga toxin and verotoxin.Specificity :The rat monoclonal antibody 38.13 recognizes CD77 (globotriaosylceramide Gb3); a neutral glycosphingolipid expressed mainly on the surface of B cell populations; such as germinal center B cells and Burkitt´s lymphoma cells.
Immunogen:
Daudi cell line (Burkitt´s lymphoma)
Purification:
Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody