Anti-FoxP3 Purified
Product Sizes
0.1 mg
£610.00
30-2739-0.1MG
About this Product
- SKU:
- 30-2739
- Additional Names:
- forkhead box P3 Scurfin; JM2; AIID; IPEX; PIDX; XPID; DIETER
- translate.label.attr.clone:
- 3G3
- Clonality:
- Monoclonal
- Extra Details:
- FoxP3 (forkhead box protein 3); a highly conserved forkhead/winged-helix transcription factor; plays a crucial role in maintaining immune homeostasis by governing the development and function of regulatory T cells. It is constitutively expressed at high level in CD25+ CD4+ Treg cells and at low level in a CD25- CD4+ Treg cell subset. Defects in gene encoding FoxP3 protein cause the scurfy phenotype in mice; and in human the IPEX syndrome (immune dysfunction; polyendocrinopathy; enteropathy; X-linked syndrome); also known as X-linked autoimmunity-allergic dysregulation (XLAAD) syndrome.Specificity :The mouse monoclonal antibody 3G3 recognizes N-terminal region of FoxP3; a 47-55 kDa transcription factor (intracellular antigen); which is the master regulator in the development and function of regulatory T cells.
- Format:
- Purified
- Immunogen:
- Full-length His-tagged recombinant murine FoxP3
- Purification:
- Purified by protein-A affinity chromatography.
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
