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Anti-Galectin-3 Purified (Clone M3/38)

Product Sizes
0.1 mg
£595.00
30-2738-0.1MG
About this Product
SKU:
30-2738
Additional Names:
lectin; galactose binding; soluble 3 Mac-2; GBP; Gal-3; L-34
translate.label.attr.clone:
M3/38
Clonality:
Monoclonal
Extra Details:
Galectin-3 is a galactose-binding lectin; which modulates intercellular interactions and interactions of the cell with ECM; as well as it is a nuclear protein and a component of inner mitochondrial membrane. Galectin-3 binds IgE; and takes part in formation of immunological synapse. It is detected cytoplasmatically in adenomas and carcinomas by immunohistochemistry. It is expressed in colonic and intestinal epithelium; papillary and follicular carcinomas; neoplastic astrocytes; inflammatory macrophages; and some lymphocytes. Upregulation of galectin-3 is involved in cancer progression and metastasis. Specificity :The rat monoclonal antibody M3/38 recognizes an epitope within amino acids 40-100 in N-terminal domain of murine galectin 3; a 35 kDa lectin expressed both intracellularly; and after its secretion also on the cell surface.
Format:
Purified
Immunogen:
murine galectin-3
Purification:
Purified by protein-G affinity chromatography.
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Lectins