Anti-Hu Granzyme A Purified
Product Sizes
0.1 mg
£541.00
30-2737-0.1MG
About this Product
- SKU:
- 30-2737
- Additional Names:
- Granzyme A HFSP; CTLA3; GrA
- translate.label.attr.clone:
- CB9
- Clonality:
- Monoclonal
- Extra Details:
- Granzyme A is a serine protease expressed in the cytoplasmic granules of T cells and NK cells. Vectorial secretion of perforin and granzymes is responsible for their granule-mediated cytotoxicity. Similarly to granzyme B; granzyme A acts to destroy the target cells by proteolysis of their particular components. In case of granzyme A the targets are e.g. APEX1 (it destroys its oxidative repair activity); and nucleosome assembly protein SET (it disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA).Specificity :The mouse monoclonal CB9 recognizes granzyme A; a 28 kDa serine protease expressed intracellularly in activated Tc cells and NK cells.
- Format:
- Purified
- Immunogen:
- Full length human granzyme A
- Purification:
- Purified by protein-A affinity chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
