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Antibodies

Anti-Hu HER3 Purified

Product Sizes
0.1 mg
£541.00
30-2736-0.1MG
About this Product
SKU:
30-2736
Additional Names:
erb-b2 receptor tyrosine kinase 3 ERBB3; FERLK; LCCS2
translate.label.attr.clone:
H3Mab-17
Clonality:
Monoclonal
Extra Details:
HER3 (ERBB3) is a transmembrane protein of the epidermal growth factor receptor family; although it does not have an active tyrosine kinase domain. It can bind its ligand; but for further signaling it needs heterodimerization with other receptor tyrosine kinases of EGFR family. Overexpression of HER3 has been observed in many carcinomas. Activity of HER3 can be modulated by one of its isoforms; that is secreted from the cell; as its lacks the transmembrane domain.Specificity :The mouse monoclonal antibody H3Mab-17 recognizes an extracellular epitope on human HER3; a member of EGFR family of receptor tyrosine kinases; which is overexpressed in many cancers.
Format:
Purified
Immunogen:
HER3-transfected CHO cells
Purification:
Purified by protein-A affinity chromatography.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody