Anti-Ms MHC Class II Biotin
Product Sizes
0.1 mg
£551.00
30-2729-0.1MG
About this Product
- SKU:
- 30-2729
- translate.label.attr.clone:
- M5/114
- Clonality:
- Monoclonal
- Conjugate:
- Biotin
- Extra Details:
- MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells; such as macrophages; dendritic cells and B cells. Before their exposition on the cell surface; the MHC class II molecules react with endocytosed exogenous antigens; which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long.Specificity :The rat monoclonal antibody M5/114 reacts with murine MHC class II glycoproteins. It recognizes a shared extracellular determinant on I-Ab; I-Ad; I-Aq; and I-Ed; I-Ek alloantigens; but it does not react with I-Af; I-Ak; I-As. This antibody can inhibit I-A-restricted T cell responses of the H-2b; H-2d; H-2q; H-2u but not H-2f; H-2k; H-2s haplotypes.
- Immunogen:
- Activated C57BL/6 mouse spleen cells
- Purification:
- Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
