Anti-Hu SIGLEC8 PE
Product Sizes
100 Tests
£620.00
30-2719-100TESTS
About this Product
- SKU:
- 30-2719
- Additional Names:
- sialic acid binding Ig like lectin 8 SAF2
- translate.label.attr.clone:
- 7C9
- Clonality:
- Monoclonal
- Conjugate:
- PE
- Extra Details:
- SIGLEC8 is a sialic acid binding lectin similar to CD33. In its cytoplasmic comain it contains an immunoreceptor tyrosine-based inhibitory motif (ITIM); and a motive similar to a binding site for SLAM-associated protein. SIGLEC8 is expressed e.g. in lymph nodes and spleen. It is an eosinophil marker; although it can be found also on the surface of mast cells. Crosslinking of SIGLEC8 leads to apoptosis. Soluble form of SIGLEC8 can be foud in human serum; especially in case of eosinophil-associated diseases. Specificity :The mouse monoclonal antibody 7C9 recognizes an extracellular epitope of SIGLEC8; an eosinophil marker; expressed e.g. in lymph nodes and spleen.
- Immunogen:
- Extracellular domain of human SIGLEC8 fused with Fc fragment of human IgG1
- Purification:
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:30-2719.jpg
