Anti-Hu CD272 PE
Product Sizes
100 Tests
£620.00
30-2705-100TESTS
About this Product
- SKU:
- 30-2705
- Additional Names:
- BTLA1
- translate.label.attr.clone:
- MIH26
- Conjugate:
- PE
- Extra Details:
- Specificity : The mouse monoclonal antibody MIH26 recognizes an extracellular epitope of CD272; a transmembrane glycoprotein serving as a negative regulator of the activation in various leukocyte types. CD272; a type I transmembrane glycoprotein; contains in its intracellular domain two ITIM sequences; which are upon CD272 triggering phosphorylated and recruit SHP phosphatases to attenuate cell activation. CD272 is expressed on B and T lymphocytes; NK cells; dendritic cells; and macrophages; and its ligand is CD270. Defects in CD272-CD270 inhibitory mechanism lead to autoimmune diseases. Overexpression of CD272 is a marker of tolerant T cells.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- cells transfected with human CD272
- Isotype:
- Mouse IgG2a kappa
- Purification:
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
