Alexa Fluor 647 conjugated Anti-Galectin-9 Monoclonal Antibody (Clone:9M1-3)
Product Sizes
100 tests
£649.00
30-2698AF647-100TESTS
About this Product
- SKU:
- 30-2698AF647
- Additional Names:
- HUAT; LGalS9A; LEG9
- translate.label.attr.clone:
- 9M1-3
- Clonality:
- Monoclonal
- Extra Details:
- Galectin-9 is a glycan-binding protein; which is expressed in three main isoforms of 49 aa; 27 aa; and 15 aa. It can be detected on the cell surface; as well as intracellularly; or in a secreted form. On the cell surface; galectin-9 plays roles in contacts with other cells and with extracellular matrix. It is expressed on multiple cell types; but mainly on Treg cells; activated Th cells and some cancers. Its secreted form acts like a cytokine with immunomodulatory and immunosuppresive functions. Massive and inadequate production of galectin-9; associated with some viral infections or cancers; can counteract immune reactions to these illnesses. High levels of galectin-9 expression lead to poor prognosis of cancer patients. Specificity: The mouse monoclonal antibody 9M1-3 recognizes an epitope within C terminus of human galectin-9; a glycan-binding protein expressed mainly on activated Th cells and FoxP3+ Treg cells.
- Host:
- Mouse
- Immunogen:
- Recombinant M-type splicing variant of human galectin 9
- Isotype:
- Mouse IgG1 kappa
- Purification:
- Purified antibody is conjugated with Alexa Fluor 647 NHS ester under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
