Anti-Hu Galectin-9 Purified (clone:9M1-3)
Product Sizes
0.1 mg
£541.00
30-2698-0.1MG
About this Product
- SKU:
- 30-2698
- Additional Names:
- HUAT; LGalS9A; LEG9
- translate.label.attr.clone:
- 9M1-3
- Clonality:
- Monoclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Galectin-9 is a glycan-binding protein; which is expressed in three main isoforms of 49 aa; 27 aa; and 15 aa. It can be detected on the cell surface; as well as intracellularly; or in a secreted form. On the cell surface; galectin-9 plays roles in contacts with other cells and with extracellular matrix. It is expressed on multiple cell types; but mainly on Treg cells; activated Th cells and some cancers. Its secreted form acts like a cytokine with immunomodulatory and immunosuppresive functions. Massive and inadequate production of galectin-9; associated with some viral infections or cancers; can counteract immune reactions to these illnesses. High levels of galectin-9 expression lead to poor prognosis of cancer patients. Galectin-9 is a glycan-binding protein; which is expressed in three main isoforms of 49 aa; 27 aa; and 15 aa. It can be detected on the cell surface; as well as intracellularly; or in a secreted form. On the cell surface; galectin-9 plays roles in contacts with other cells and with extracellular matrix. It is expressed on multiple cell types; but mainly on Treg cells; activated Th cells and some cancers. Its secreted form acts like a cytokine with immunomodulatory and immunosuppresive functions. Massive and inadequate production of galectin-9; associated with some viral infections or cancers; can counteract immune reactions to these illnesses. High levels of galectin-9 expression lead to poor prognosis of cancer patients. Specificity : The mouse monoclonal antibody 9M1-3 recognizes an epitope within C terminus of human galectin-9; a glycan-binding protein expressed mainly on activated Th cells and FoxP3+ Treg cells.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- recombinant M-type splicing variant of human galectin 9
- Isotype:
- Mouse IgG1 kappa
- Purification:
- Purified by protein-A affinity chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze. Phosphate buffered saline (PBS); pH 7.4; 15 mM sodium azide.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Lectins
- Manufacturer's Data Sheet:1.jpg
