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Antibodies

Anti-Hu TCR Vdelta2 PE

Product Sizes
100 Tests
£620.00
30-2695-100TESTS
About this Product
SKU:
30-2695
translate.label.attr.clone:
B6
Clonality:
Monoclonal
Conjugate:
PE
Extra Details:
The mouse monoclonal antibody B6 recognizes an extracellular epitope of human TCR Vdelta2; which is expressed on the majority of gamma/delta T cells. TCR Vdelta2 is a variant of TCR delta chain; that is present on a major subset of human gamma/delta T cells. TCR Vgamma9/Vdelta2 (or Vgamma2/Vdelta2) T cells are able to recognize and kill various tumor cells; as this receptor heterodimer binds to certain phosphoantigens; expressed by tumors. They can recognize these antigens in an MHC-unrestricted manner. Similarly to NK cells; Vdelta2 T cells express MHC I receptors and killer Ig-like receptors; that are involved in tumor recognition and cytolysis. The potently cytotoxic subset of them is identified by cell surface expression of polysialyated CD56.
Immunogen:
human recombinant TCR Vdelta2
Isotype:
Mouse IgG1 kappa
Purification:
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure-2: Flow cytometry multicolor surface staining of human lymphocytes stained using anti-human TCR Vdelta2 (B6) PE antibody (10 μl reagent / 100 μl of peripheral whole blood) and anti-human CD3 (UCHT1) APC antibody (10 μl reagent / 100 μl of peripheral whole blood).
Figure-3:Separation of human TCR Vdelta2 positive lymphocytes (red-filled) from TCR Vdelta2 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human TCR Vdelta2 (B6) PE antibody (10 μl reagent / 100 μl of peripheral whole blood).
Figure-3:Separation of human TCR Vdelta2 positive lymphocytes (red-filled) from TCR Vdelta2 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human TCR Vdelta2 (B6) PE antibody (10 μl reagent / 100 μl of peripheral whole blood).