Anti-Mouse CD106 Antibody (Clone : 429 (MVCAM.A))
Product Sizes
0.1 mg
£482.00
30-2665-0.1MG
About this Product
- SKU:
- 30-2665
- Additional Names:
- Vcam-1;vascular cell adhesion molecule 1
- translate.label.attr.clone:
- 429 (MVCAM.A)
- Clonality:
- Monoclonal
- Extra Details:
- CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival; as well as in adhesion; transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation; tumour cells can use overexpressed VCAM-1 to escape T cell immunity.Specificity : The rat monoclonal antibody 429 (also known as MVCAM.A) recognizes an extracellular epitope of murine CD106; a 100-110 kDa type I membrane protein of the immunoglobulin superfamily; a crucial mediator of leukocyte adhesion; and a costimulation molecule.
- Format:
- Purified
- Immunogen:
- Murine preadipose cell line PA6
- Isotype:
- Rat IgG2a kappa
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies
- Manufacturer's Data Sheet:1.jpg
