Anti-Human CD146 PerCP (Clone : P1H12)
Product Sizes
100 tests
£639.00
30-2651-100TESTS
About this Product
- SKU:
- 30-2651
- Additional Names:
- MelCAM; MCAM; MUC18;melanoma cell adhesion molecule
- translate.label.attr.clone:
- P1H12
- Clonality:
- Monoclonal
- Extra Details:
- CD146; also known as MCAM (melanoma cell adhesion molecule) or MUC18; is a heavily glycosylated transmembrane glycoprotein with more than 50% of the mass from carbohydrates. It is expressed on epithelial and endothelial cells; fibroblasts; multipotent mesenchymal stromal cells; activated T cells and activated keratinocytes; and on some cancer cells; especially melanoma. The presence of CD146 on circulating blood cells has been confined to the activated T cells rather than circulating endothelial cells. CD146 mediates heterophilic cell adhesion and regulates monocyte transendothelial migration. Specificity : The mouse monoclonal antibody P1H12 recognizes an extracellular epitope of CD146; a 118 kDa transmembrane glycoprotein expressed on epithelial and endothelial cells; fibroblasts; multipotent mesenchymal stromal cells; melanoma cells; activated T cells and activated keratinocytes.
- Immunogen:
- cultured human umbilical cells
- Isotype:
- Mouse IgG1
- Purification:
- The purified antibody is conjugated with PerCP under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reactivities:
- Human, Mouse, Rabbit
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:30-2561.jpeg
