Anti-Human CD15 FITC (Clone : MMA)
Product Sizes
100 tests
£581.00
30-2649-100TESTS
About this Product
- SKU:
- 30-2649
- Additional Names:
- Lewis x Blood Group antigen; Le(x); SSEA-1; 3-fucosyl-N-acetyllactosamine;
- translate.label.attr.clone:
- MMA
- Clonality:
- Monoclonal
- Conjugate:
- FITC
- Extra Details:
- CD15 (Lewis X; Le(x); stage specific embryonic antigen-1; SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids; glycoproteins and proteoglycans of various cell types; e.g. granulocytes; mast cells; monocytes; macrophages; cells of gastric mucosa; nervous system or various tumour cells. There are several variants of Lewis x; such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation; based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin´s disease.Specificity : The mouse monoclonal antibody MMA reacts with an extracellular epitope of CD15; a cell membrane 3-fucosyl-N-acetyllactosamine (3-FAL) strongly expressed on granulocytes; monocytes; macrophages; mast cells; it is also present on Langerhans cells and some myeloid precursors cells. This antibody is a superior reagent for identifying of Hodgkin´s lymphoma.
- Immunogen:
- U937 histiocytic lymphoma cells
- Isotype:
- Mouse IgM kappa
- Purification:
- The purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
