Anti-Human CD172b Antibody (Clone : B4B6)
Product Sizes
0.1 mg
£532.00
30-2630-0.1MG
About this Product
- SKU:
- 30-2630
- Additional Names:
- SIRPB1;signal regulatory protein beta 1
- translate.label.attr.clone:
- B4B6
- Clonality:
- Monoclonal
- Extra Details:
- CD172b; the signal-regulatory protein beta (SIRP beta) is a disulfide-linked homodimer expressed on myeloid cells including monocytes and dendritic cells. Similarly to CD172a; it serves as a negative regulator of tyrosine kinase-coupled signaling processes. Unlike CD172a; the CD172b protein does not possess the cytoplasmic domain; but instead its transmembrane domain can interact with another transmembrane protein DAP-12; which contains ITAM sequences in its intracellular domain and links CD172b to the downstream signaling molecules. The result is e.g. regulation of neutrophil transepithelial migration.Specificity : The mouse monoclonal antibody B4B6 recognizes an extracellular epitope of CD172b; an approximately 50 kDa transmembrane glycoprotein expressed on myeloid cells.
- Format:
- Purified
- Immunogen:
- NIH-3T3 cells transfected with human CD172b
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies
- Manufacturer's Data Sheet:1.jpg
