Anti-Mouse CD2 PE (Clone : RM2-5)
Product Sizes
0.1 mg
£620.00
30-2628-0.1MG
About this Product
- SKU:
- 30-2628
- Additional Names:
- LFA-2; Ly37; Ly-37;CD2 molecule
- translate.label.attr.clone:
- RM2-5
- Clonality:
- Monoclonal
- Conjugate:
- PE
- Extra Details:
- CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover; T cell activation induces increased CD2 expression and its lateral mobility; making easier contact between CD2 and CD58. Subsequently; T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact; thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.Specificity : The rat monoclonal antibody RM2-5 recognizes an extracellular epitope of CD2; a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells; also expressed by all thymocytes.
- Immunogen:
- Murine thymocytes
- Isotype:
- Rat IgG2b lambda
- Purification:
- The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
