Anti-Mouse CD2 Low Endotoxin Antibody (Clone : RM2-5)
Product Sizes
0.1 mg
£521.00
30-2626-0.1MG
About this Product
- SKU:
- 30-2626
- Additional Names:
- LFA-2; Ly37; Ly-37;CD2 molecule
- translate.label.attr.clone:
- RM2-5
- Clonality:
- Monoclonal
- Extra Details:
- CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover; T cell activation induces increased CD2 expression and its lateral mobility; making easier contact between CD2 and CD58. Subsequently; T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact; thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.Specificity : The rat monoclonal antibody RM2-5 recognizes an extracellular epitope of CD2; a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells; also expressed by all thymocytes.
- Format:
- Low Endotoxin
- Immunogen:
- Murine thymocytes
- Isotype:
- Rat IgG2b lambda
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies
- Manufacturer's Data Sheet:download_pdf.php
