Anti-Human CD205 APC (Clone : HD30)
Product Sizes
100 tests
£620.00
30-2624-100TESTS
About this Product
- SKU:
- 30-2624
- Additional Names:
- DEC-205; LY75; CLEC13B;lymphocyte antigen 75
- translate.label.attr.clone:
- HD30
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- CD205; also known as DEC-205; is an endocytic receptor of macrophage mannose receptor family. This 205 kDa C-type lectin transmembrane protein mediates adsorptive uptake and its intracellular domain contains coated pit localization sequence and distal acidic motif; which is required for recycling beyond early endosomes through deeper MHC II+ late endosomes and lysosomes. This unique pathway of receptor-mediated uptake proves to be necessary for presentation of antigenic peptides at low doses of ligand. CD205 is responsible for uptake and processing of captured antigens for dendritic cells.Specificity : The mouse monoclonal antibody HD30 recognizes an extracellular epitope of CD205; an approx. 200 kDa C-type lectin transmembrane protein of the MMR (macrophage mannose receptor) family; expressed at high levels on dendritic cells and thymic epithelial cells; and at low levels on lymphocytes; NK cells and monocytes.
- Immunogen:
- Recombinant Fc-tagged human CD205
- Isotype:
- Mouse IgG1 kappa
- Purification:
- The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
