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Antibodies

Anti-Human CD206 APC (Clone : 15-2)

Product Sizes
100 tests
£620.00
30-2622-100TESTS
About this Product
SKU:
30-2622
Additional Names:
MMR; MRC1; CLEC13DL;mannose receptor C-type 1
translate.label.attr.clone:
15-2
Clonality:
Monoclonal
Conjugate:
APC
Extra Details:
CD206 (macrophage mannose receptor; MMR); also known as mannose receptor C1 (MRC1); is a type I transmembrane glycoprotein serving as pattern recognition receptor for carbogydrate groups on the surface of bacteria; fungi and other pathogens. Expressed mainly on tissue macrophages and dendritic cells; CD206 mediates endocytosis of these pathogens and presentation of their antigens to the adaptive immune system. CD206 can also be detected in a soluble form in human plasma and is elevated in patients with acute sepsis.Specificity : The mouse monoclonal antibody 15-2 (also known as MR15-2) recognizes an extracellular epitope of CD206 (macrophage mannose receptor; MMR); a 162-175 kDa type I transmembrane protein expressed mainly on macrophages; dendritic cells and hepatic or lymphatic endothelial cells; but not on monocytes.
Immunogen:
Purified human mannose receptor
Isotype:
Mouse IgG1 kappa
Purification:
The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2 : Flow cytometry multicolor surface staining pattern of human stimulated (GM-CSF + IL-4) peripheral blood mononuclear cells stained using anti-human CD206 (15-2) APC antibody (10 µl reagent per milion cells in 100 µl of cell suspension) and anti-human CD11c (BU15) PE antibody (20 µl reagent per milion cells in 100 µl of cell suspension).
Figure 3 :Separation of human CD206 positive CD11c positive dendritic cells differentiated upon monocyte stimulation (GM-CSF + IL-4) (red-filled) from non-stimulated lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human stimulated (GM-CSF + IL-4) peripheral blood mononuclear cells stained using anti-human CD206 (15-2) APC antibody (10 µl reagent per milion cells in 100 µl of cell suspension).
Figure 3 :Separation of human CD206 positive CD11c positive dendritic cells differentiated upon monocyte stimulation (GM-CSF + IL-4) (red-filled) from non-stimulated lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human stimulated (GM-CSF + IL-4) peripheral blood mononuclear cells stained using anti-human CD206 (15-2) APC antibody (10 µl reagent per milion cells in 100 µl of cell suspension).