Anti-Human CD21 PerCP (Clone : LT21)
Product Sizes
100 tests
£620.00
30-2621-100TESTS
About this Product
- SKU:
- 30-2621
- Additional Names:
- CR2; C3DR2; CVID7; SLEB9;complement C3d receptor 2
- translate.label.attr.clone:
- LT21
- Clonality:
- Monoclonal
- Conjugate:
- PerCP
- Extra Details:
- CD21 (complement receptor 2; CR2) binds C3 complement fragments; especially its breakdown fragments; which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes; survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.Specificity : The antibody LT21 reacts with an extracellular epitope of CD21 (CR2); a 145 kDa transmembrane glycoprotein (complement C3d receptor - C3dR) expressed on B lymphocytes; follicular dendritic cells; some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells.
- Immunogen:
- IM9 human B-lymphoblastoid cell line
- Isotype:
- Mouse IgG1
- Purification:
- The purified antibody is conjugated with PerCP under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
