Anti-Human CD253 APC (Clone : 2E5)
Product Sizes
0.1 mg
£620.00
30-2613-0.1MG
About this Product
- SKU:
- 30-2613
- Additional Names:
- TRAIL; Apo-2 ligand; Apo-2L; TNFSF10; APO2L; TNLG6A;TNF superfamily member 10
- translate.label.attr.clone:
- 2E5
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- Human CD253 / TRAIL (TNF-Related Apoptosis Inducing Ligand); also called Apo2; is a type II membrane protein from the TNF family. TRAIL is a cytotoxic protein which activates rapid apoptosis in tumor cells; but not in normal cells. TRAIL-induced apotosis; is achieved through binding to two dealth-signaling receptors; DR4 (CD261 / TRAIL-R1) and DR5 (CD262 / TRAIL-R2).Specificity : The antibody 2E5 reacts with an extracellular epitope within C-terminal half of TRAIL (APO-2L); a 21 kDa cytotoxic protein; activator of rapid apoptosis in tumor cells. TRAIL is mainly expressed in spleen; lung; prostate and also in many other tissues.
- Immunogen:
- Recombinant soluble fragment (aa 95-281) of human TRAIL.
- Isotype:
- Mouse IgG1
- Purification:
- The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
