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Antibodies

Anti-Human CD267 APC (Clone : 1A1)

Product Sizes
100 tests
£620.00
30-2607-100TESTS
About this Product
SKU:
30-2607
Additional Names:
RYZN; TACI; CVID2; IGAD2; TNFRSF14B;TNF receptor superfamily member 13B
translate.label.attr.clone:
1A1
Clonality:
Monoclonal
Conjugate:
APC
Extra Details:
CD267 / TACI (Transmembrane Activator Calcium modulator and cyclophilin ligand Interactor); a TNFR superfamily transmembrane protein; is expressed on B cells (predominantly on CD27+ memory cells); multiple myeloma cells and B cell chronic lymphocytic leukemia (B-CLL). Its triggering leads to activation of the transcription factors NFAT; AP1; and NF-kappa-B. It plays a crucial role in humoral immunity. Mutations in CD267 are associated with common variable immunodeficiency and IgA deficiency.Specificity : The rat monoclonal antibody 1A1 recognizes an extracellular epitope of CD267 / TACI; a 32 kDa type III transmembrane protein expressed by B cells and possibly by some activated T cells.
Immunogen:
CD267-transfected RBL cells
Isotype:
Rat IgG2a kappa
Purification:
The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2 : Flow cytometry multicolor surface staining pattern of human lymphocytes using anti-human CD267 (1A1) APC antibody (10 µl reagent / 100 µl of peripheral whole blood) and anti-human CD19 (LT19) PE antibody (20 µl reagent / 100 µl of peripheral whole blood) antibody.
Figure 3 :Separation of human CD267 positive CD19 positive B cells (red-filled) from human CD267 negative CD19 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD267 (1A1) APC antibody (10 µl reagent / 100 µl of peripheral whole blood).
Figure 3 :Separation of human CD267 positive CD19 positive B cells (red-filled) from human CD267 negative CD19 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD267 (1A1) APC antibody (10 µl reagent / 100 µl of peripheral whole blood).